The TADS trial closed enrollment on July 31st, 2003.
What Is TADS?....
The Treatment for Adolescents with Depression Study, TADS, is a research study of treatments for Major Depressive Disorder in teenagers. TADS will compare the short- and longer-term effectiveness of medication and psychotherapy for depression, also known as Major Depressive Disorder, in teenagers. For teens treated in TADS, the trial is designed to provide best-practice practical care for depression. It is our hope that the overall study results will improve the future care of adolescents with depression.
disorder (MDD) is a mood disorder that can alter thoughts, feelings and behavior.
In particular, teens with MDD often:
- are sad,
blue, irritable and/or complain that nothing is fun anymore
- have trouble
sleeping, low energy, poor appetite and trouble concentrating
socially withdrawn or perform more poorly in school
- can be
of teenagers have major depression at any one time. Among teens, girls
are more often affected than boys. MDD frequently interferes with home,
school and family life, including causing a lot of family stress. Suicide
is the third leading cause of death among teenagers, with about half of
these associated with depression. This makes depression a common and serious
illness that is important to identify and treat early in the course of
the disease. To understand which treatments work best for which depressed
teenagers, TADS is comparing different treatments for major depression
in teens, with the goal of improving the treatment and outcomes of young
persons with this disorder.
Information About Depression: The following two links provide comprehensive
general information about depression.
have entered a web site that describes an NIMH-funded collaborative
study on the treatment of adolescents with depression. If you are
seeking immediate help for treatment of depression, we recommend
that you contact your clinician or your nearest emergency room.
This web site is not set up to provide help or advice to individuals
about their depression, nor to family members or friends of individuals
you are interested in getting general information about depression,
you can visit the following web site:
web site is created solely for the purposes of providing background
information about the study and having researchers provide input
to the design.
web site does not provide a chat room and individual queries will
not receive a response. Any message posted on this web site is not